8/7c - We find ourselves inside the mind of Lee as he awakens after a bicycle accident in New York unable to move or communicate verbally. From his unique perspective, we hear Lee’s inner thoughts as House, injured in a motorcycle accident, occupies the hospital bed next to him.
9/8c - Charlotte, an older woman who has spent the last six months taking care of her husband Eddie, is rushed to Princeton Plainsboro for immediate treatment after collapsing from respiratory failure at Eddie's deathbed.
8/7c - House and the team take on the case of Nick, a book editor who loses his inhibition and starts insulting coworkers at a dinner party one night before falling ill.
9/8c - House and the team take on the case of Morgan who works in a nursing home with a pet cat who only sleeps next to people if they are about to die – and does so with alarmingly accuracy.
8/7c - When a priest who runs a homeless shelter sees a bleeding Jesus hovering at this doorstep, he is admitted to the ER. House takes on the case as a distraction for the team while he confronts Foreman and Thirteen about their relationship.
9/8c - The team encounters a teenage boy who collapsed from severe pelvic pain after playing basketball. Tests reveal the boy has genetic mosaicism, or both male and female DNA, and the boy’s parents inform House and the team that the boy is unaware of his condition.
8/7c - Cuddy decides to spend more time at home to take care of her newly adopted baby and passes some of her day-to-day responsibilities to Cameron, including supervising House. Cameron is forced to play House's games and becomes involved in a power struggle as he and the team take on the case of a Special Education teacher who collapsed after spitting up blood in the middle of class.
9/8c - House and the team take on the case of a woman who collapsed in the middle of a cooking class and they soon learn she is highly renowned cancer researcher who recently gave up her entire career in order to pursue her own personal happiness.
8/7c - House and the team take on the case of a high-profile fitness trainer who collapses while shooting an infomercial.
9/8c - At Cameron's urging, House and the team take on the case of a man living with such severe chronic pain that he tries to kill himself, unable to go on after living for years without a diagnosis or any relief from his suffering.
8/7c - The team takes on the case of a 16-year-old factory manager who fell ill when her lungs suddenly filled with fluid while at work. The teenager informs House and team that she is an emancipated minor living on her own and supporting herself, and has ever since her parents passed away.
9/8c - A gun-wielding man from the waiting room at the Princeton-Plainsboro clinic takes House, Thirteen and several patients from the waiting room hostage in Cuddy’s office. The man claims to be sick with a long undiagnosed illness and demands medical attention from the best doctor in the hospital, threatening to kill any hostages necessary along the way.
8/7c - The team takes on the case of a dreary middle-aged man who has been experiencing unexplained recurring blackouts and time lapses.
9/8c - When an agoraphobic man falls mysteriously ill and adamantly refuses to leave his home to get treatment at the hospital, House and the team go to him to figure out what might be wrong.
8/7c - When House receives word that his father has passed away, he brushes off the news and dismissed the idea of going to the funeral.
9/8c - When a woman with whom Thirteen had a one-night stand falls ill and has seizures at Thirteen’s apartment after a night of partying, Thirteen accompanies the woman to Princeton- Plainsboro where House and the team take on her case.
8/7c - When several people die suddenly and without warning five years after receiving transplants from a single organ donor, House and the team rush to save the only two surviving recipients.
9/8c - House and the team take on the case of a struggling artist who has been painting bizarre portraits. His undiagnosed illness is distorting his perception, threatening to undermine his career, his relationships and everything else in his life.
8/7c - House remains inhibited by injuries sustained from a bus accident that has also left a victim rapidly deteriorating from a mysterious condition.
9/8c - Eight weeks after the death of his girlfriend, Amber, Wilson is still mourning her death, and his relationship with his best friend House is shattered.
8/7c - House is convinced one of the actors on his favorite soap opera has a serious medical condition after observing his symptoms on television.
9/8c - House finds himself dazed, confused and covered in blood after surviving a bus accident that left dozens seriously injured.
8/7c - House and Thirteen treat a newly converted Hasidic Jewish woman.
9/8c - House assigns Foreman to give the team performance reviews while he treats a patient who is just too nice.