Severide (Taylor Kinney) and Stella (Miranda Rae Mayo) are on the lookout for a very unstable Grant (guest star Guy Burnet), who left Chicago Med without notice. Now that Dawson (Monica Raymund) is responsible for Louie, she questions her dangerous career path as a firefighter. Casey (Jesse Spencer) continues his work as Alderman but his relationship with his political consultant, Susan Weller (guest star Lauren Stamile), cools. Problems continue for Borrelli (Steven R. McQueen), who still blames Chief Boden (Eamonn Walker) for the death of his brother, and the situation reaches a boiling point.
Casey (Jesse Spencer) and Dawson (Monica Raymund) find themselves unexpectedly caught in the middle of a potential political mess. Stella (Miranda Rae Mayo) is left to make a serious decision about her ex-boyfriend. While responding to an auto accident, members of truck and squad find themselves in the middle of a dangerous situation. Elsewhere, Severide (Taylor Kinney) befriends a famous socialite (guest star Scott Elrod) that might distract him from his duties at 51, while Brett (Kara Killmer) and Mouch (Christian Stolte) set aside their writing differences for the greater good.